DOES ADHERENCE TO THE MEDITERRANEAN DIETARY PATTERN REDUCE ASTHMA SYMPTOMS IN CHILDREN? A SYSTEMATIC REVIEW OF OBSERVATIONAL STUDIES

Asthma remains a global public health problem of epic proportions, especially in children and adolescents. Asthma is a complex respiratory disorder characterized by symptoms that include wheezing, chest tightness, coughing (especially at night) and breathlessness resulting from air flow obstruction triggered by the interaction of genetic and environmental factors.

Maria M Papamichael, Catherine Itsiopoulos1, Nugroho H Susanto and Bircan Erbas, School of Allied Health, Department of Rehabilitation, Nutrition and Sport, La Trobe University, Melbourne, VIC 3086, Australia: School of Psychology and Public Health, Department of Public Health, La Trobe University, Melbourne, Australia

Abstract
Objective: The purpose of the present systematic review was to synthesize evidence from the literature to assess efficacy of the Mediterranean dietary pattern in childhood asthma.

Design/Setting: A systematic search of six databases, three clinical trial registries and hand-search of peer-reviewed articles was conducted up to 29 October 2016. Inclusion
criteria included exposure to a Mediterranean dietary pattern, measurement of asthma symptoms and study population of children aged <18 years. Quality assessment was conducted. Due to significant heterogeneity, meta-analysis was not feasible.

Results:
Of the 436 articles identified, after removal of duplicates and based on inclusion criteria, fifteen observational studies conducted in Mediterranean and
non-Mediterranean countries were relevant. No randomized controlled trials were retrieved. Twelve studies reported an inverse association between adherence to a Mediterranean dietary pattern and asthma in children, two studies showed no association and one study showed an increase in asthma symptoms. In fourteen out of fifteen studies, quality assessment checks revealed good reliability and
validity among study methodologies.

Conclusions:
The current systematic review revealed a consistent inverse relationship (protective) between a Mediterranean dietary pattern and asthma in children. Future well-designed randomized controlled trials are needed to provide solid evidence. Nevertheless, the existing level of evidence adds to the public health message relating to the beneficial effects of a Mediterranean-type diet in children suffering with asthma.

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Papamichael 2017 PHN Med diet SR